|
PSYCHIATRY QUIZ |
| After
reading carefully select the most appropriate answer by encircling the
alphabetical letter. |
| 1 One
of the following cyclic antidepressants the one with maximum
anticholinergic side effect is: |
|
a) |
Imipramine |
|
b) |
Nortriptyline |
|
c) |
Amitriptyline |
|
d) |
Doxepin |
| 2
Metabolic- Endocrine effects of Lithium include all the following except |
|
a) |
Hypothyroidism |
|
b) |
Hyperparathyroidism |
|
c) |
Hypoparathyroidism |
|
d) |
Painless thyroiditis causing transient Hyperthyroidism followed by
Hypothyroidism. |
| 3 The
benzodiazepine with shortest half life is |
|
a) |
Lorazepam |
|
b) |
Oxazepam |
|
c) |
Diazepam |
|
d) |
Nitrazepam |
| 4
Virtually all benzodiazepines are highly lipophilic. But the one which is
water soluble is |
|
a) |
Chloediazepoxide |
|
b) |
Lorazepam |
|
c) |
Diazepam |
|
d) |
Nitrazepam |
| 5 The
antidepressant which is most likely to lower the seizure threshold is |
|
a) |
Fluoxetine |
|
b) |
Bupropion |
|
c) |
Mianserine |
|
d) |
Trazodone |
| 6 The
combined use of Verapamil and Lithium can result in |
|
a) |
Degreases serum Lithium level |
|
b) |
Increases serum Lithium level |
|
c) |
No change in serum Lithium level |
|
d) |
Severe hypotension |
| 7 The
differential diagnosis of recurrent abdominal pain in an elevenyearr old
child includes all of the following except. |
|
a) |
Acute intermittent porphyria |
|
b) |
Subacute sclerosing panencephalitis |
|
c) |
Meckel's Diverticulam |
|
d) |
Sbdomonal epilepsy |
| 8
Teratogenic risk for Psychotropic drugs is high between |
|
a) |
First and third week |
|
b) |
Third and eighth week |
|
c) |
Tenth and fouteenth week |
|
d) |
After fourteenth week |
| 9
Seizures associated with frontal lobe epilepsy are most frequently the
result of |
|
a) |
Postnatal trauma |
|
b) |
Malignant tumors |
|
c) |
Tuberous sclerosis |
|
d) |
Vascular malformation of unknown etiology |
| 10
Suggested Pharmacotherapies for Alzheimer's disease Dementia include the
use of neurotropics. All of the following are neurotropics except |
|
a) |
Amyloid beta protien |
|
b) |
Somatostatin |
|
c) |
Nerve growth factor |
|
d) |
L-acetyl carnitin |
| 11 The
association of D2DR gene is confirmed in |
|
a) |
Alcoholism |
| b) |
Alzheimer's |
| c) |
Schizophrenia |
| d) |
Depression |
| 12
Compared to high potency phenothiazines, low potency aliphatic and
piperidine phenotiazines are more likely to produce |
|
a) |
Orthoatatic hypotension |
|
b) |
Anticholinergic side effects |
|
c) |
Exxtrapiramidal reactions |
|
d) |
Sedation |
| 13 The
chance of relapse in the first year in a patient with a history of
recurrent Schizophrenic episodes on stopping antipsychotic medication is
approximately |
|
a) |
10% |
|
b) |
30% |
|
c) |
65% |
|
d) |
95% |
| 14
Weight gain is reported with most antidepressant medication except |
|
a) |
Nortriptyline |
|
b) |
Maprotiline |
|
c) |
Fluoxetine |
|
d) |
Trazodone |
| 15
Buspirone has high affinity towards |
|
a) |
5HT1A receptor |
|
b) |
5HT1B receptor |
|
c) |
5HT1C receptor |
|
d) |
5HT1D receptor |
| 16 The
medical conditions wherein Lithium holds some promise include all of the
following except |
|
a) |
Herpes Simplex |
|
b) |
Menier's Syndrome |
|
c) |
Hyperthyroidism |
|
d) |
Hyperparathyroidism |
| 17 The
percentage of excepted omprovement on Impramine in enuretic patient is |
|
a) |
10% fewer wet nights |
|
b) |
30% fewer wet nights |
|
c) |
60% fewer wet nights |
|
d) |
80% fewer wet nights |
| 18 A
patient on Lithium therapy is prescribed ACE inhibitors (Captopril/
Enalapril) by her cardiologist for the management of hypertention. This
interaction may result in |
|
a) |
Indreased serum lithium level |
|
b) |
Degreases serum lithium level |
|
c) |
No change serum lithium level |
|
d) |
Severe hypotention |
| 19 A
Todd's paralysis |
|
a) |
Lasts
less than 12 hours |
|
b) |
May persist for weeks |
|
c) |
Is a 'false localising sign' |
|
d) |
Does not have the same significance as a focal seizure |
| 20
Focal seizures are particularly common manifistation |
|
a) |
In a glioma |
|
b) |
In a convexity menigioma |
|
c) |
In an ependymoma |
|
d) |
Following cerebral infarction due to occlusion of the middle cerebral
artery. |
| 21 A
patient with acute intermittent porphyria develops seizures. The safest
anticonvulsant would be |
|
a) |
Valproate |
|
b) |
Phenobarbitone |
|
c) |
Paraldehyde |
|
d) |
Phenytoin |
| 22 Eczema,
blonde hair, blue eyes and mental retardation are features of |
|
a) |
Phenylketonuria |
|
b) |
Tuberous sclerosis |
|
c) |
Toxoplasmosis |
|
d) |
Cretinism |
| 23 All
of the following are correct regarding lithium except |
|
a) |
Absorption complete in 8 hours |
|
b) |
Protien bound |
|
c) |
Excreted almost entirely by kidneys |
|
d) |
Inhibits adenly
cyclase, reducing intracellular levels of cAMP |
| 24 The
hypotensive effect of some of the antidepressants is due to |
|
a) |
Alpha 1-adrenoreceptor blockade |
|
b) |
Alpha 2-adrenoreceptor blockade |
|
c) |
Beta 2-adrenoreceptor blockade |
|
d) |
Histamine H- 1 receptor blockade |
| 25
Granular deposits in the cornea and lens in patients treated with long
term chlorpromazine occur in about |
|
a) |
5-10% |
|
b) |
20-30% |
|
c) |
30-40% |
|
d) |
40-50% |
| 26
Allof the following are correct regarding ophthalmoplegic migraine except |
|
a) |
Ophthalmoplegia on the same side as the headache |
|
b) |
Headache
may last for several days |
|
c) |
More common in males |
|
d) |
Visual prodromes are rare |
| 27 A
patient had sudden onset of hemiplegia and contralateral
ophthalmoplegia. The lesion is most likely in the |
|
a) |
Pons |
|
b) |
Mesencephalon |
|
c) |
Frontal lobe |
|
d) |
Lateral medulla |
| 28 The
antidepressant with reuptake inhibition property of both dopamine and
norepinephrine uptake is |
|
a) |
Amineptine |
|
b) |
Nomifensine |
|
c) |
Amoxapine |
|
d) |
Mianserine |
| 29 All
of the following are true regarding Huntington's chorea except |
|
a) |
Dementia |
|
b) |
Progressive choreiform movements |
|
c) |
Necrosis of globus pallidus |
|
d) |
Atrophy of the caudate nucleus |
| 30 All
of the following are side effects of valproate except |
|
a) |
Alopecia |
|
b) |
Weight loss |
|
c) |
Coagulopathy |
|
d) |
Tremor |
| 31
Oxaprotitline is a |
|
a) |
Monocyclic antidepressant |
|
b) |
Bicyclic antidepressant |
|
c) |
Tricyclic antidepressant |
|
d) |
Tetracyclic antidepressant |
| 32
Fross alterations characteristic of Pick's disease include all the
following except |
|
a) |
Sever so called 'Knife-edge' atrophy |
|
b) |
Severeatrophy of the posterior 3/5 of the superior temporal gyrus. |
|
c) |
Relative preservation of the [re and post central gyri |
|
d) |
Atrophy of the straitum |
| 33 Cell
bodies of neurons using betaendrofin as neurotranmitter are located in the
|
|
a) |
Substantia nigra |
|
b) |
Arcuate nucleus of the hypothalamus |
|
c) |
Periacquequctal gray matter |
|
d) |
Dorsal horn of spinal cord |
| 34 EEG
manifastation of autonomic seizures are |
|
a) |
14 and 6HZ positive |
|
b) |
Temporal lobe spikes or generalised spike and waves |
|
c) |
Spike and wave phantoms |
|
d) |
Amall sharp spikes |
| 35 The
antidepressant action of clenbuterol and salbutamol is due to |
|
a) |
Reuptake inhibition of neurotransmitter |
|
b) |
Alpha adrenoceptor blockade |
|
c) |
Down regulaton of beta adrenoceptor |
|
d) |
Enhancement of serotonin uptake |
| 36 All
of the following have an excitatory effects on the postsynaptic cell
except |
|
a) |
Increased permeability to ca ++ |
|
b) |
Slow increased permeability to Na ++ |
|
c) |
Decreased permeability to K + |
|
d) |
Increased permeability to K + |
| 37
Benzodiazepines modulate the synaptic action of |
|
a) |
Glycine |
|
b) |
Dopamine |
|
c) |
Acetylcholine |
|
d) |
GABA |
| 38 The
commonest symptom of increased intracranial Pressure in childhood is |
|
a) |
Blurred vision |
|
b) |
Stupor |
|
c) |
Vomiting |
|
d) |
Ataxia |
| 39
Olfactory hallucinations occure with lesion of the |
|
a) |
Parietal lobe |
|
b) |
Olfactory tubercle |
|
c) |
Temporal lobe in the region uncus |
|
d) |
Occipital lobe |
| 40 PET
imagine in OCD patients revealed brain dysfunction in certain brain areas.
The area implicated in the Secondary major depression often complicating
OCD is |
|
a) |
Orbital Prefrontal cortex |
|
b) |
Antirolateral Prefrontal cortex |
|
c) |
Straitum |
|
d) |
Temporal cortex |
| 1
(a) 2 (c) 3 (b) 4 (b) 5
(b) 6 (a) 7 (b) 8 (b) 9
(a) 10 (b) 11 (a) |
| 12
(d) 13 (c) 14 (c) 15 (a)
16 (d) 17 (c) 18 (a) 19
(a) 20 (b) |
| 21
(c) 22 (a) 23 (b) 24 (b)
25 (b) 26 (c) 27 (b) 28
(b) 29 (c) |
| 30
(b) 31 (d) 33 (b) 34 (b) 35
(c) 36 (d) 37 (d) 38 (c)
39 (c) 40 (b) |
|
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